Multilocus
Part of speech: adjective
Definitions
- Relating to or involving multiple specific positions in a genetic sequence or map, typically used in the context of inheritance or molecular biology
- Pertaining to several distinct locations within a genome or set of genes, often studied to understand complex traits or diseases
- Concerning various discrete points on chromosomes or DNA that are analyzed together to assess genetic variation or linkage patterns
Etymology: "Multilocus" is a technical coinage from modern genetics, built from two Latin pieces: the prefix "multi-", from "multus" meaning "many," and "locus," the Latin word for "place." Its parts are plain and transparent, so the interest lies in the sense of "place" they carry. "Locus" was adopted into English as a term in its own right, and the Latin word traces back to an older root meaning "place" or "spot," which also gave English words like "stall" and "stellar" through a distant ancestor. The combined word describes a set of separate positions on a chromosome or strand of DNA that researchers examine together. Each "locus" is a fixed spot where a gene or marker sits, so "multilocus" means many such spots studied as a group rather than one at a time. Analyses of this kind help geneticists track how variants are inherited together and how closely related populations are.
Synonyms: polygenic, multigenic, multiple-loci
Antonyms: monogenic, single-locus