Isocyanides
Part of speech: noun
Definitions
- A class of organic compounds containing a -N≡C functional group, typically known for their toxic properties and ability to react with various nucleophiles
- These compounds are characterized by a carbon atom triple-bonded to nitrogen, which can exhibit important reactions in organic synthesis
- Often recognized in the context of industrial chemistry, isocyanides can function as intermediates in the production of pharmaceuticals and other chemicals
Etymology: The plural "isocyanides" simply follows the singular "isocyanide", which is built from two parts: "iso-", from Ancient Greek "ísos" meaning "equal", and "cyanide". The "iso-" prefix in chemistry signals that a compound has the same atoms as another but arranged differently, and here it marks the isocyanide group as a structural rearrangement of the cyanide group. In the -N≡C arrangement, the nitrogen sits where the carbon sits in a cyanide, so these compounds are isomers of nitriles, which is why the name pairs the two.