Integrins
Part of speech: noun
Definitions
- A type of proteins found on cell surfaces that enable adhesion between cells and their external environment, influencing interactions and signaling processes
- Proteins located on cell membranes that assist in connecting cells to one another and to the extracellular matrix, playing essential roles in cellular interactions and functions
- Proteins embedded in the cell membrane that facilitate binding between the cell and its surroundings, thereby regulating communication and attachment
Etymology: "Integrins" is the plural of "integrin", and the singular form is a deliberate coinage from the late twentieth century rather than an ancient or inherited term. The name was built from the Latin "integer", meaning whole or entire, combined with a suffix that chemists and biologists use to name proteins. The idea behind it was that these molecules integrate the inside and outside of a cell, linking its internal skeleton to the material surrounding it. Because the word is a modern technical formation, its parts are easy to read: the root carries the sense of wholeness, and the ending marks it as a protein. Its meaning is therefore tied to function rather than to any older everyday sense, so the name describes what the molecules do in the cell, not a traditional concept that was later applied to them.