Decorin

Part of speech: noun

Definitions

1. A protein-bound molecule found in the extracellular matrix of connective tissue that helps regulate collagen fibril formation and binds growth factors
2. A proteoglycan present in the connective tissue of animals, important for organizing collagen fibers and influencing cell signaling
3. A small leucine-rich molecule in the body's connective tissue matrix that assists in shaping collagen structure and modulating tissue growth

Etymology: Decorin is a protein, and its name is a deliberately constructed one: it combines "decorate" with the chemical suffix "-in," which is the ending chemists attach to a great many substances. The name reflects the molecule's role. Decorin sits in the extracellular matrix, the material surrounding cells in connective tissue, where it binds to collagen fibrils and regulates how they are assembled. Because it coats and organises these fibres, its name suggests a decorator working on the scaffolding of the body.